Brufen 400 mg 30 Tablets
Ibuprofen
A Propionic acid derivative non-steroidal anti-inflammatory drug that inhibits the prostaglandin synthesis by non-selectively inhibiting COX enzymes thus reducing inflammatory pain and fever.
Indications:
• Pain and inflammation.
• Fever.
• Postoperative analgesia.
• Dental pain.
• Migraine.
• Osteoarthritis.
Points of interest:
• To reduce stomach upset, take this tablet with food.
• Do not take aspirin for pain relief while using this medication.
• Do not take this medication if you are dehydrated, due to severe vomiting or diarrhea.
• Stop this medication and tell your doctor immediately if you develop swollen ankles, difficulty in breathing, chest pain, black stools, or dark vomit.
How to use:
2 tablets every 8 hours after meals.
Active Ingredients:
Ibuprofen.
Side effects:
• Nausea.
• Diarrhea.
• Ulceration.
• Fluid retention.
• Hypersensitivity reactions.
Cautions :
• GIT disorders and chronic inflammatory intestinal disease. These conditions may be exacerbated.
• Caution is required prior to starting the treatment in patients with hypertension or heart failure. Renal function may deteriorate.
• Renal and hepatic dysfunction.
• Elderly at increased risk of serious consequences of adverse reactions, especially GIT bleeding and perforation which may be fatal.
• Bronchospasms may be precipitated in patients suffering from asthma.
• Contraindicated in patients with asthma.
• Contraindicated in patients with peptic ulcer.
Interactions:
• Methotrexate: the excretion of methotrexate is reduced by ibuprofen
• Baclofen: the excretion of baclofen is reduced by ibuprofen
• Tacrolimus: the concomitant used is associated with an increased risk of nephrotoxicity.
• Voriconazole or fluconazole: plasma concentrations of ibuprofen increased by voriconazole .
• Aspirin: ibuprofen reduces the antiplatelet effect of aspirin.
Quantity:
30 Tablets.
How To Store:
room temperature.
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