Coveram 5 mg / 5 mg 30 Tablets
Coveram contain Amlodipine + perindopril arginine.
Amlodipine a dihydropyridine Calcium-Channel Blocker which blocks the cellular influx of calcium ions that is responsible for maintaining the plateau phase of the action potential in the myocardial muscles thus reducing the strength of contractility and cardiovascular tone.
Perindopril is an angiotensin converting enzyme (ACE) inhibitor that inhibits the conversion of angiotensin I to angiotensin II by blocking the activity of the converting enzyme. The inhibition of ACE will result in decreased concentrations of Angiotensin II which will then result in decreased vasoconstriction activity because Angiotensin II receptors are deactivated. It also results in decreased water retention because aldosterone production is terminated.
Active ingredients:
Amlodipine, Perindopril Arginine.
Indications:
Coveram tablets used for:
• Hypertension.
• Angina.
How to use:
Take coveram as per as direction of doctor.
Side effects of coveram:
• Headache.
• Dizziness.
• Hypotension.
• Palpitations.
Cautions:
• Severe hepatic impairment.
• May be used coveram tablets with patients with renal impairment at normal doses.
• Increase the dose with elderly patients must take place with care.
Interactions of Coveram:
• Grapefruit Juice: Increases plasma concentration of the drug.
• Sildenafil: enhanced hypotensive effect of the drug when given with Sildenafil.
• Simvastatin: increases the risk of myopathy when used with the drug.
• Clopidogrel: the drug may decreases clopidogrel effect.
Quantity:
30 Tabs
Store at room temperature
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